Resume

Positions

2016 – current Post-doctoral fellow at the Centre for Genomics and Oncological Research (Genyo), Spain. Mentors: Dr. Per Anderson and Dr. Francisco Martín.

2016 – current Post-doctoral researcher at the Biomedical Research Center, University of Granada, Spain. Mentors: Dr. Pablo Galindo-Moreno and Francisco O’Valle Ravassa.

2014 – 2016 Post-doctoral fellow at the Institute of Parasitology and Biomedicine “López-Neyra” (IPBLN). Spanish National Research Council (CSIC). Mentors: Prof. José Mariano Ruiz de Almodóvar and Dr. Javier Oliver Pozo.

2013 – 2014 Post-doctoral researcher at the Biomedical Research Center, Universidad de Granada, Spain. Mentor: Prof. José Mariano Ruiz de Almodóvar.

Education

2012 PhD in Cellular and Molecular Immunology. University of Granada, Spain. Advisors: Prof. José Mariano Ruiz de Almodóvar, PhD and José-luis Linares, PhD

2008 Master’s in Cellular and Molecular Immunology. University of Granada, Spain. Advisors: Prof. José Mariano Ruiz de Almodóvar, PhD and José-luis Linares, PhD

2004 Licentiate and Bachelor in Biological Sciences. State University of Paraíba, Campina Grande, Brazil. Advisors: Francisco Brito and Napoleão E. de Macêdo Beltrão, PhD

Publications

Farias, V. A., F. O’Valle, B. Alonso, T. Schmidt, J. López-Peñalver, A. Nieto, A. M. Santos, B. I. Fernández, A. Guerra-Librero, C. Ruiz-Ruiz, C. Ruiz de Almodóvar, F. J. Oliver, and J. M. Ruiz de Almodóvar (2015). “Human mesenchymal stem cells enhance the systemic effects of radiotherapy”. Oncotarget 6:31164-31180. doi: 10.18632/oncotarget.5216.

Lara, P. C., J. J. López-Peñalver, V. A. Farias, M. C. Ruiz-Ruiz, F. J. Oliver, and J. M. R. de Almodóvar (2015). “Direct and bystander radiation effects: a biophysical model and clinical perspectives.” Cancer letters 356.1, pp. 5–16. doi: 10.1016/j.canlet.2013.09.006.

Farias, V. A., J. J. López-Peñalver, J. Sirés-Campos, M. V. López-Ramón, C. Moreno- Castilla, F. J. Oliver, and J. M. Ruiz de Almodóvar (2013). “Growth and spontaneous differentiation of umbilical-cord stromal stem cells on activated carbon cloth”. Journal of Materials Chemistry B 1.27, pp. 3359–3368. doi: 10.1039/C3TB20305K.

Gómez-Millán, J., I. S. S. Katz, V. A. Farias, J.-L. Linares-Fernández, J. López- Peñalver, G. Ortiz-Ferrón, C. Ruiz-Ruiz, F. J. Oliver, and J. M. Ruiz de Almodóvar (2012). “The importance of bystander effects in radiation therapy in melanoma skin-cancer cells and umbilical-cord stromal stem cells.” eng. Radiother Oncol 102.3, pp. 450–458. doi: 10.1016/j.radonc.2011.11.002.

Farias, V. A., J.-L. Linares-Fernández, J. López-Peñalver, J. A. Payá-Colmenero, G. Ortiz-Ferrón, E. L. Duran, R. M. Fernández, E. G. Olivares, F. O’Valle, A. Puertas, F. J. Oliver, and J. M. Ruiz de Almodóvar (2011). “Human umbilical cord stromal stem cell express CD10 and exert contractile properties.” Placenta 32.1, pp. 86–95. doi: 10.1016/j.placenta.2010.11.003.

Peñalver, J. L., J.-L. Linares-Fernández, V. A. Farias, M. V. López-Ramón, M. Tassi, F. J. Oliver, C. Moreno-Castilla, and J. M. Ruiz de Almodóvar (2009). “Activated carbon cloth as support for mesenchymal stem cell growth and differentiation to osteocytes”. Carbon 47.15, pp. 3574 –3577. issn: 0008-6223. doi: 10.1016/j.carbon.2009.08.016.

Severino, L. S., M. I. L. Silva, V. A. Farias, N. E. M. Beltrão, and G. G. Cardoso (2006). “Sexual expression of castor influenced by fertilizer and mepiquat chloride”. Portuguese. Revista ciência agronômica 37.3, pp. 339–344. [PDF]

Severino, L. S., N. E. M. Beltrão, G. G. Cardoso, V. A. Farias, and C. L. D. de Lima (2002). “Análise do Crescimento e Fenologia do Gergelim Cultivar Cnpa G4”. Portuguese. Revista Brasileira de Oleaginosas e Fibrosas 6.3, pp. 599–608. [PDF]

Conference communications

Nieto, A, V. A. Farias, J. López-Peñalver, A Fernández, M Tassi, A. Santos, F O’Valle, and J. M. Ruiz de Almodóvar (2015). “Magnetic resonance imaging in the follow up of melanocytic tumors treated with hMSC and radiotherapy”. I Congreso Ibérico de Ciencias del Animal de Laboratorio / I Congresso Iberico de Ciências de Animais de Laboratório. Laboratory Animals. Vol. 49. 3S. Sociedad Española para las Ciencias del Animal de Laboratorio & Sociedade Portuguesa de Ciéncias em Animais de Laboratório. Cáceres, p. 58. doi: 10.1177/0023677215609551[Poster doi: 10.6084/m9.figshare.5331385.v1] First prize for poster presentation.

Farias, V. A., J. Sirés-Campos, J. J. López-Peñalver, C. Moreno- Castilla, and J. M. Ruiz de Almodóvar (2013). “Activated-carbon cloth supports umbilical-cord stromal stem cells growth and differentiation”. Annual World Conference on Carbon (Carbon 2013). Brazilian Carbon Association (ABCarb). Rio de Janeiro. [Extended abstract] [Presentation (Prezi)] doi: 10.6084/m9.figshare.5331421.v1

Sirés, J., V. A. Farias, J. López, and J. M. Ruiz de Almodóvar (2012). “Modulation of UCSSC osteogenesis in a carbon-based scaffold”. Histology and Histopathology. Vol. 27. supplement 1. Granada, pp. 110–111. [Poster doi: 10.6084/m9.figshare.5331472.v1]

Gómez-Millán, J., I. S. S. Katz, V. A. Farias, J.-L. Linares-Fernández, J. López- Peñalver, G. Ortiz-Ferrón, C. Ruiz-Ruiz, F. J. Oliver, and J. M. Ruiz de Almodóvar (2012). “The importance of bystander effects in radiation therapy in melanoma skin-cancer cells and umbilical-cord stromal stem cells.” Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. Vol. 102. 3, pp. 450–8. doi: 10.1016/j.radonc.2011.11.002. [Poster]

Farias, V. A., J. Gómez-Millán, I. S. S. Katz, J.l. Linares-Fernández, J. López- Peñalver, G. Ortiz-Ferrón, C. Ruiz-Ruiz, F. J. Oliver, and J. M. Ruiz de Almodóvar (2011). “The importance of bystander e ects in melanoma skin-cancer cells and umbilical-cord stromal stem cells”. X Aporeunión. Red española de apoptosis APORED. Cuenca. [Oral presentation]

Lopez-Peñalver, J. J., J. L. Linares-Fernández, V. A. Farias, M. V. López-Ramón, F. J. Oliver-Pozo, C. Moreno-Castilla, and J. M. Ruiz de Almodovar-Rivera (2010). “Telas de carbón activado como soporte para el crecimiento de células madre”. Spanish. X Reunión del grupo español del carbón. Grupo Español del Carbón. Girona. [Oral presentation]

Farias, V. A., J. L. Fernández, S.Rios-Arrabal, J.López-Peñalver, l.A. Payá-Colmenero, G.Ortíz-Ferrón, E. Leno-Duran, R. Muñoz-Fernández, E. Garcia-Olivares, F. O’Valle, A . Puertas, F. J. Oliver-Pozo and J. M. Ruiz de Almodóvar (2009) “Characterization of Human Umbilical Cord Matrix Stem Cells Under Improved Culture Conditions”. Human Gene Therapy. 20(9): 1048-1093. doi: 10.1089/hum.2009.1722. [Poster]

Torres, B., B. Hortal, M. I. Núñez, V. A. Farias, D. León, S. R. Arrabal, and M. Villalobos (2009). “Aportación Clínica de Marcadores Tumorales Epigenéticos en Cáncer de Pulmón”. Spanish. XIII Congreso SESPAS: Tiempos para la Salud Pública. Gaceta Sanitaria. Vol. 23. P-019. SESPAS. Sevilla: Elsevier España, pp. 121–121. [Poster]

Grants

Science without Boarders Postdoctoral grant (2014 – 2016). Brazilian National Council for Scientific and Technological Development (CNPq).

Research projects

Spanish National Plan for Scientific and Technical Research and Innovation (2013-2015). Spanish Ministry of Economy and Competitiveness #SAF2012-40011-C02-02 60,000 EUR. Principal Investigator: José Mariano Ruiz de Almodóvar.

Spanish National Plan for Scientific and Technical Research and Innovation (2010-2013). Spanish Ministry of Economy and Competitiveness #SAF2009-13281-CO2-02 121,000 EUR. Principal Investigator: José Mariano Ruiz de Almodóvar.

Patents

Uso de células madre mesenquimales (MSCs) activadas mediante radiación en la elaboración de un medicamento para el tratamiento del cáncer. Farias, V. d. A., J. López-Peñalver, F. J. Oliver, and J. M. Ruiz de Almodóvar (2014). Pat. Pending (ES).

Umbilical-cord stromal stem cells grown and differentiated on an activated-carbon cloth: the importance of surface porosity. Farias, V. d. A., J. López-Peñalver, J. Sirés-Campos, C. Moreno-Castilla, F. J. Oliver, and J. M. Ruiz de Almodóvar (2013). Pat. P9210ES00 (ES).

Theses

Farias, V. de A. (2012, February 17). Obtención y caracterización de células del estroma del cordón umbilical humano. Universidad de Granada, Granada. ISBN: 9788490280690

Farias, V. de A. (2008). Células madre perivasculares de cordón umbilical humano: obtención, cultivo, caracterización y potencialidades de diferenciación. Universidad de Granada, Granada.

Theses mentored

Velazquez-Liñán, J. (2017). “Characterisation of Outer Membrane Vesicles derived from Bacteria Related to Periodontitis”. Universidad de Granada.

Barba-Domínguez, F. (2017). “Factores locales y sistémicos de relevancia en las enfermedades periodontal y aterosclerótica”. Universidad de Granada.

Capitán-Sobrino, D. (2017). “Caracterización de células estromales de pulpa dental”. Universidad de Granada.

Carrasco-Carmona A. (2017). “Caracterización de células estromales multipotentes mesenquimales (MSCs) derivadas de hueso injertado”. Universidad de Granada.

Pacheco, R. (2015). “Tumor cell death caused by the mesenchymal stem cell radiation conditioned medium”. Universidad de Granada.

Samper, M. (2015). “Antitumoral potential of radiation activated mesenchymal stem cells: bystander effect”. Universidad de Granada.

Guerra-Librero, A. (2014). “Tumor cell and radiation-activated mesenchymal stem cell interaction”. Universidad de Granada.

Seguí, R. (2014). “Irradiated MSC conditioned medium influence on tumor cell growth”. Universidad de Granada.

Alonso, B. (2014). “Mesenchymal stem cell activated by radiation”. Universidad de Granada.

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